Description

5-Fluoro-O4-(2,4,6-Trimethylphenyl)-2'-Deoxyuridine is a specialized nucleoside analogue derivative, designed for advanced research and development applications. This compound is valued for its role as a key synthetic intermediate and a potential building block in the development of novel therapeutic agents and diagnostic tools. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on antiviral, anticancer, and molecular probe development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate DNA/RNA metabolism and related biological pathways.
• Probe Development: Acts as a building block for creating labeled or modified nucleosides used in diagnostic assays and molecular imaging.
• Antiviral Agent Research: Investigated for its potential activity against viral polymerases due to its fluorinated and modified uracil structure.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of therapeutic compounds.
• Academic Synthesis: Used in advanced organic chemistry laboratories for teaching and methodology development in heterocyclic and nucleoside chemistry.

Basic Information

Product Name	5-Fluoro-O4-(2,4,6-Trimethylphenyl)-2'-Deoxyuridine
CAS No.	141120-63-0
Molecular Formula	C20H23FN2O5
Molecular Weight	390.41 g/mol
Synonyms	5-Fluoro-2'-deoxy-O4-(2,4,6-trimethylphenyl)uridine; 2'-Deoxy-5-fluoro-O4-(mesityl)uridine; 5-Fluoro-O4-mesityl-2'-deoxyuridine; 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoro-4-(2,4,6-trimethylphenoxy)pyrimidin-2(1H)-one; 5-F-dU-O4-Mes; FDU-O4-Mes
EINECS	Contact for details

Quality Control

Our 5-Fluoro-O4-(2,4,6-Trimethylphenyl)-2'-Deoxyuridine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and specifications can be tailored to meet specific research or development project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.