Description

2-Aminoindan-2-Phosphonic Acid is a specialized organophosphorus compound featuring a unique indane scaffold. This structure is of significant interest for its potential as a key synthetic intermediate and a pharmacophore in medicinal chemistry research. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel bioactive molecules. The compound is supplied with a CAS Registry Number of 141120-17-4.

Application

This phosphonic acid derivative serves as a versatile building block in advanced chemical synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, particularly those targeting enzyme inhibition.
• Chemical Biology Probe: Used to study biological pathways and protein-ligand interactions due to its phosphonate moiety mimicking phosphate groups.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and material science applications.
• Academic & Industrial R&D: Serves as a critical reagent for methodological development and exploratory synthesis in organic and medicinal chemistry laboratories.

Basic Information

Product Name	2-Aminoindan-2-Phosphonic Acid
CAS No.	141120-17-4
Molecular Formula	C9H12NO3P
Molecular Weight	213.17 g/mol
Synonyms	2-Amino-2,3-dihydro-1H-indene-2-phosphonic Acid; 2-Aminoindan-2-phosphonate; 1H-Indene-2-phosphonic acid, 2-amino-2,3-dihydro-; (2-Amino-2,3-dihydro-1H-inden-2-yl)phosphonic Acid; 2-Amino-2-phosphonoindane; Aminoindanphosphonic Acid
EINECS	Contact for details

Quality Control

Our 2-Aminoindan-2-Phosphonic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.