Description

S6-(2,4-Dinitrophenyl)-N2-Phenylacetyl-2''-Deoxythioguanosine is a sophisticated, chemically modified nucleoside derivative designed for advanced research and development applications. This compound is critical for scientists working in medicinal chemistry and biochemistry, particularly in the development of novel therapeutic agents and molecular probes. It serves as a key synthetic intermediate or building block for researchers in pharmaceutical development, biotechnology, and academic institutions focused on nucleoside-based drug discovery and nucleic acid chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside analogs with potential antiviral or anticancer activity.
• Biochemical Research: Used in the study of enzyme mechanisms, particularly those involving nucleoside processing and modification.
• Probe Development: Serves as a precursor for creating labeled or tagged nucleosides for diagnostic assays and molecular imaging.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the properties of therapeutic nucleosides.
• Antisense Oligonucleotide Synthesis: A potential modified monomer for the construction of specialized oligonucleotides with enhanced properties.

Basic Information

Product Name	S6-(2,4-Dinitrophenyl)-N2-Phenylacetyl-2''-Deoxythioguanosine
CAS No.	141076-16-6
Molecular Formula	C25H21N7O8S
Molecular Weight	579.55 g/mol
Synonyms	2'-Deoxy-6-[(2,4-dinitrophenyl)thio]-N2-(phenylacetyl)guanine; 2'-Deoxy-6-(2,4-dinitrophenylthio)-N2-phenylacetylguanosine; N2-Phenylacetyl-6-(2,4-dinitrophenylthio)-2'-deoxyguanosine; S6-DNP-N2-Phenylacetyl-2'-deoxyguanosine; DNP-Thioguanosine Derivative; Modified 2'-Deoxyguanosine; Thioguanosine Intermediate
EINECS	Contact for details

Quality Control

Our S6-(2,4-Dinitrophenyl)-N2-Phenylacetyl-2''-Deoxythioguanosine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.