Description

2-Hexynyl-5'-n-Ethylcarboxamidoadanosine is a specialized nucleoside analog with a modified adenine base and sugar moiety, designed for high-affinity receptor binding. This compound is critical for advanced biochemical research and pharmaceutical development, particularly in the study of adenosine receptor signaling pathways. It serves as a valuable tool compound for researchers and developers in pharmaceutical R&D, life science research, and diagnostic reagent formulation, enabling the exploration of new therapeutic targets.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the synthesis of novel adenosine receptor agonists/antagonists.
• Biochemical Assay Development: Used as a high-affinity ligand in receptor binding studies and competitive assays to characterize adenosine receptor subtypes (e.g., A1, A2A).
• Life Science Research: A crucial tool for investigating the role of adenosine signaling in physiological and pathological processes, such as neurotransmission, immune response, and cardioprotection.
• Diagnostic Reagent Manufacturing: Potential use in the formulation of specialized kits for cellular pathway analysis and receptor profiling.
• Academic Research: Employed in university and institutional labs for fundamental studies in medicinal chemistry and molecular pharmacology.
• Preclinical Studies: Serves as a candidate molecule for in vitro and in vivo efficacy testing in disease models related to inflammation, ischemia, and CNS disorders.

Basic Information

Item	Detail
Product Name	2-Hexynyl-5'-n-Ethylcarboxamidoadanosine
CAS No.	141018-30-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-Hex-1-ynyl-N-ethyl-5'-carboxamidoadenosine; 2-Hexynyl-NECA; 2-Hexynyl-5'-(N-ethylcarboxamido)adenosine; 2-(1-Hexyn-1-yl)-N-ethyladenosine-5'-uronamide; NECA derivative; Adenosine receptor ligand; 2-Alkynyl-NECA analog
EINECS	Contact for details

Quality Control

Every batch of 2-Hexynyl-5'-n-Ethylcarboxamidoadanosine is produced and controlled under a strict quality management system. We guarantee high-purity material suitable for research applications, with comprehensive analytical testing including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.