Description

5-Aminolevulinic Acid Hexyl Ester is a lipophilic ester derivative of the endogenous photosensitizer precursor 5-aminolevulinic acid (ALA). This chemical modification enhances its cellular uptake and bioavailability, making it a critical intermediate in photodynamic therapy (PDT) research and development. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic manufacturers, and academic institutions focused on oncology and dermatology for the targeted treatment of various cancers and skin conditions.

Application

• Photodynamic Therapy (PDT) Research: A key prodrug used in the development of novel PDT agents for cancer treatment, including skin, bladder, and brain cancers.
• Dermatology: Investigated for use in the photodynamic treatment of actinic keratosis, acne, and other dermatological conditions.
• Diagnostic Imaging: Serves as a precursor for protoporphyrin IX (PpIX), used in fluorescence-guided surgery to visualize tumor margins.
• Biochemical Research: Used as a tool compound to study the heme biosynthesis pathway and cellular mechanisms of photosensitization.
• Pharmaceutical Intermediate: An essential building block in the synthesis of more complex, targeted photodynamic therapeutic agents.
• Veterinary Medicine: Potential application in PDT treatments for animal cancers.

Basic Information

Product Name	5-Aminolevulinic Acid Hexyl Ester
CAS No.	140898-97-1
Molecular Formula	C11H21NO3
Molecular Weight	215.29 g/mol
Synonyms	5-ALA Hexyl Ester; Hexyl 5-Aminolevulinate; 5-Amino-4-oxopentanoic Acid Hexyl Ester; ALA-Hex; Hexyl Aminolevulinate; 5-ALA Hexylester; 5-Aminolaevulinic Acid Hexyl Ester
EINECS	Contact for details

Quality Control

Our 5-Aminolevulinic Acid Hexyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.