Description

(3A,5B,6B,7B,12B)-3,6,7,12-Tetrahydroxy-Cholan-24-Oic Acid CAS NO 140852-41-1 is a high-purity, multi-hydroxylated bile acid derivative, a critical intermediate in advanced pharmaceutical synthesis. Its precise stereochemistry and functional group array make it a valuable building block for developing novel therapeutic agents and biochemical research tools. This compound is essential for manufacturers and research institutions focused on metabolic disease research, steroid chemistry, and the development of new drug candidates.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of novel bile acid analogs and steroidal drugs.
• Biochemical Research: Used as a reference standard or probe in studies of bile acid metabolism, liver function, and nuclear receptor (e.g., FXR) signaling pathways.
• Metabolic Disease Studies: Applied in research models for cholestasis, gallstone formation, and other metabolic disorders.
• Chemical Synthesis: Serves as a chiral template for the synthesis of complex, biologically active molecules due to its defined stereocenters.
• Reference Standard: High-purity grade is used for analytical method development, validation, and quality control in pharmaceutical laboratories.

Basic Information

Product Name	(3A,5B,6B,7B,12B)-3,6,7,12-Tetrahydroxy-Cholan-24-Oic Acid
CAS No.	140852-41-1
Molecular Formula	C24H40O6
Molecular Weight	424.57 g/mol
Synonyms	3α,6α,7α,12α-Tetrahydroxy-5β-cholan-24-oic Acid; 3α,6α,7α,12α-Tetrahydroxy-5β-cholanoic Acid; Tetrahydroxycholanic Acid; 5β-Cholan-24-oic acid, 3α,6α,7α,12α-tetrahydroxy-; 3,6,7,12-Tetrahydroxycholanic Acid
EINECS	Contact for details

Quality Control

Our (3A,5B,6B,7B,12B)-3,6,7,12-Tetrahydroxy-Cholan-24-Oic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.