Description

Nikkomycin S(X) CAS NO 140447-97-8 is a specialized nucleoside-peptide antibiotic belonging to the nikkomycin family, known for its potent and specific inhibitory activity against chitin synthase. This targeted mechanism makes it a valuable tool compound for research and development in the life sciences. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical sectors for antifungal studies, enzyme inhibition assays, and as a lead structure for novel therapeutic agents.

Application

• Antifungal Research: Used as a reference standard and active agent in studies targeting chitin-containing fungi, aiding in the discovery of new fungicides and antifungal drugs.
• Enzyme Inhibition Studies: Serves as a specific inhibitor of chitin synthase in biochemical and pharmacological research to understand fungal cell wall biosynthesis.
• Pharmaceutical Development: Investigated as a potential lead compound for the development of novel therapeutic agents against fungal infections.
• Agrochemical Research: Employed in the screening and development of next-generation, targeted fungicides for crop protection.
• Microbiological Assays: Used in laboratory settings to study fungal growth dynamics and resistance mechanisms.
• Biochemical Reagent: Functions as a high-purity biochemical reagent for specialized cell biology and molecular biology experiments.

Basic Information

Product Name	Nikkomycin S(X)
CAS No.	140447-97-8
Molecular Formula	C20H25N5O10
Molecular Weight	495.44 g/mol
Synonyms	Nikkomycin SX; Nikkomycin S(X); Antibiotic S(X); S(X) Nikkomycin; Chitin Synthase Inhibitor S(X); Nucleoside-Peptide Antibiotic S(X); (2S,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl (2E)-4-{[(2S,3S)-3-[(furan-2-ylcarbonyl)amino]-2-hydroxybutanoyl]amino}-2-methylbut-2-enoate
EINECS	Contact for details

Quality Control

Our Nikkomycin S(X) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and microbiological assays for activity verification. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to air and moisture. For long-term storage, consider desiccants and under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Biological Activity	Assayed; COA provided

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.