Description

9-(C-4,T-5-Bis(Hydroxymethyl)Cyclopent-2-En-R-1-Yl)-9H-Adenine is a sophisticated nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate in the creation of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of modified nucleosides and nucleotide prodrugs. The precise stereochemistry and functional groups of this molecule make it a critical component for developing targeted, high-potency active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel antiviral drugs, particularly those targeting viral polymerases.
• Anticancer Agent Research: Used in the development of nucleoside-based chemotherapeutic agents and prodrugs designed for targeted cancer therapy.
• Prodrug Synthesis: A key building block for creating nucleotide prodrugs, which enhance the bioavailability and cellular uptake of active drug molecules.
• Biochemical Research: Employed in academic and industrial laboratories to study enzyme-substrate interactions, particularly with kinases and polymerases.
• Medicinal Chemistry: Utilized for structure-activity relationship (SAR) studies to optimize the potency and selectivity of nucleoside analogs.
• Process Chemistry Development: Acts as a starting material or intermediate in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	9-(C-4,T-5-Bis(Hydroxymethyl)Cyclopent-2-En-R-1-Yl)-9H-Adenine
CAS No.	140440-40-0
Molecular Formula	C₁₄H₁₇N₅O₂
Molecular Weight	287.32 g/mol
Synonyms	9-[(1R,4S,5R)-4,5-Bis(hydroxymethyl)cyclopent-2-en-1-yl]-9H-adenine; (1R,4S,5R)-4,5-Bis(hydroxymethyl)-2-cyclopenten-1-yl adenine; Cyclopentenyl Adenine Derivative; 9H-Adenine, 9-[(1R,4S,5R)-4,5-bis(hydroxymethyl)-2-cyclopenten-1-yl]-; BCHC-Adenine; Nucleoside Analog Intermediate; 140440-40-0; Adenine cyclopentenyl derivative
EINECS	Contact for details

Quality Control

Our 9-(C-4,T-5-Bis(Hydroxymethyl)Cyclopent-2-En-R-1-Yl)-9H-Adenine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All materials are subjected to rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing all specified parameters. Our quality commitment aligns with the standards expected for pharmaceutical intermediates in development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.