Description

Bicyclo[2.2.1]Heptane-1-Carbonyl Chloride, 7,7-Dimethyl-2,3-Dioxo-, (1S)- (9Ci) is a high-purity, chiral bicyclic acid chloride derivative, serving as a critical advanced intermediate in sophisticated organic synthesis. Its value lies in its rigid, functionalized norbornane skeleton and reactive carbonyl chloride group, enabling precise stereochemical control in the construction of complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing chiral, constrained analogs in drug discovery programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides with enhanced efficacy and environmental profiles.
• Material Science Research: Serves as a monomer or cross-linking agent for developing novel polymers with unique thermal and mechanical properties derived from the norbornane structure.
• Asymmetric Catalysis Ligand Precursor: Employed in the synthesis of chiral ligands and organocatalysts for enantioselective transformations.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, flavors, and fragrances requiring high stereochemical purity.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-1-Carbonyl Chloride, 7,7-Dimethyl-2,3-Dioxo-, (1S)- (9Ci)
CAS No.	140386-60-3
Molecular Formula	C10H11ClO3
Molecular Weight	214.65 g/mol
Synonyms	(1S)-7,7-Dimethyl-2,3-dioxobicyclo[2.2.1]heptane-1-carbonyl chloride; (1S)-1-(Chlorocarbonyl)-7,7-dimethyl-2,3-dioxobicyclo[2.2.1]heptane; (-)-7,7-Dimethyl-2,3-dioxobicyclo[2.2.1]heptane-1-carbonyl chloride; (1S)-Camphor-1-carbonyl chloride derivative; 1S-7,7-Dimethyl-2,3-dioxonorcamphor-1-carbonyl chloride; (1S)-1-Chlorocarbonyl-7,7-dimethyl-2,3-dioxonorbornane
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-1-Carbonyl Chloride, 7,7-Dimethyl-2,3-Dioxo-, (1S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee reproducible quality and performance in your processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from heat, sparks, open flames, and incompatible materials such as bases, amines, and oxidizing agents. Handle and store under an inert atmosphere (e.g., nitrogen or argon) to maximize shelf-life stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.