Description

Valproyl-Adenylic Acid is a chemically modified nucleotide analog of significant interest in advanced pharmaceutical research and development. This compound is valued for its potential role as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel therapeutics. It is primarily utilized by research institutions and pharmaceutical companies focused on developing treatments for neurological and metabolic disorders. The product is supplied to the global market with a commitment to high purity and reliable supply chain integrity.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) conditions.
• Biochemical Research: Used as a reference standard or probe in metabolic pathway studies and enzyme inhibition assays within academic and industrial R&D laboratories.
• Preclinical Development: Employed in the formulation and testing stages of new chemical entities (NCEs) during drug discovery pipelines.
• Active Pharmaceutical Ingredient (API) Synthesis: Functions as a core component in the manufacturing process of specialized prescription medications.
• Metabolite Analysis: Acts as an analytical standard in pharmacokinetic and bioanalytical studies to understand drug metabolism and disposition.

Basic Information

Product Name	Valproyl-Adenylic Acid
CAS No.	140233-88-1
Molecular Formula	C18H24N5O7P
Molecular Weight	453.39 g/mol
Synonyms	Valproyl-AMP; 5'-O-[(2-Propylpentanoyl)]adenosine monophosphate; Adenosine-5'-monophosphoric acid 5'-(2-propylpentanoate) ester; Valproyl adenosine monophosphate; Valproate-AMP conjugate; VPA-AMP; 2-Propylpentanoyl adenylate; Adenylic acid valproyl ester
EINECS	Contact for details

Quality Control

Our Valproyl-Adenylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet client-specific monograph requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.