Description

1-Allylisoguanosine is a modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a versatile building block for the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in creating next-generation nucleotide-based therapies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used in studies investigating nucleotide metabolism, enzyme inhibition, and the structure-activity relationships of modified nucleosides.
• Prodrug Synthesis: Serves as a scaffold for creating prodrugs designed to improve bioavailability and targeted delivery of active pharmaceutical ingredients (APIs).
• Antiviral Agent Development: Investigated for its potential incorporation into oligonucleotides targeting viral replication mechanisms.
• Labeled Compound Production: A starting material for synthesizing isotopically labeled (e.g., C13, N15) compounds for metabolic and pharmacokinetic studies.

Basic Information

Product Name	1-Allylisoguanosine
CAS No.	140156-26-9
Molecular Formula	C11H13N5O4
Molecular Weight	279.26 g/mol
Synonyms	9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-(prop-2-en-1-ylamino)-1H-purin-2-one; 1-Allyl-isoGuanosine; 6-Allylaminoisoguanosine; 6-Allylamino-2-hydroxy-9-β-D-ribofuranosylpurine; Allylisoguanosine; IsoGuanosine, 1-allyl-
EINECS	Contact for details

Quality Control

Our 1-Allylisoguanosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.