Description

6-Bromopicolinic Acid Chloride is a versatile and highly reactive chemical building block, primarily used as an intermediate in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 6-bromopicolinoyl moiety, a key structural motif in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bromine atom for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized picolinamide-based ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of functional organic molecules for electronic materials or polymers.
• Custom Synthesis and Contract Manufacturing: A key reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	6-Bromopicolinic Acid Chloride
CAS No.	139487-69-7
Molecular Formula	C6H3BrClNO
Molecular Weight	220.45 g/mol
Synonyms	6-Bromopyridine-2-carbonyl chloride; 2-Bromo-6-pyridinecarbonyl chloride; 6-Bromopicolinoyl chloride; 6-Bromo-2-pyridinecarboxylic acid chloride; 6-Bromopyridine-2-carboxylic acid chloride; 2-Pyridinecarbonyl chloride, 6-bromo-; 6-Bromo-2-picolinoyl chloride
EINECS	Contact for details

Quality Control

Our 6-Bromopicolinic Acid Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.