Description

Bicyclo[2.2.1]Heptane-1-Carbonyl Chloride, 7,7-Dimethyl-2,3-Dioxo- (9Ci) is a highly reactive and versatile bicyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its unique norbornane-based structure with adjacent carbonyl and oxo functionalities makes it invaluable for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those requiring rigid, bicyclic frameworks for enhanced biological activity and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where its structural motif can contribute to target specificity and environmental persistence.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal and mechanical properties.
• Asymmetric Catalysis Ligand Precursor: The scaffold is utilized to construct chiral ligands and organocatalysts for enantioselective synthesis.
• Chemical Biology Probe Development: Employed to create activity-based probes and molecular tags for studying enzyme function and protein interactions.
• Academic & R&D Laboratories: Fundamental research tool for methodological studies in organic chemistry, including new cycloaddition and annulation reactions.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Heptane-1-Carbonyl Chloride, 7,7-Dimethyl-2,3-Dioxo- (9Ci)
CAS No.	139399-01-2
Molecular Formula	C10H11ClO3
Molecular Weight	214.65 g/mol
Synonyms	7,7-Dimethyl-2,3-dioxobicyclo[2.2.1]heptane-1-carbonyl chloride; 1-Carboxy-7,7-dimethyl-2,3-dioxonorbornane chloride; 7,7-Dimethyl-2,3-dioxonorbornane-1-carbonyl chloride; Norbornane acid chloride derivative; 1-Chlorocarbonyl-7,7-dimethyl-2,3-dioxobicyclo[2.2.1]heptane; DNBC-Cl; 2,3-Dioxo-7,7-dimethylbicyclo[2.2.1]heptane-1-carbonyl chloride
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-1-Carbonyl Chloride, 7,7-Dimethyl-2,3-Dioxo- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including NMR, HPLC, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment. We adhere to cGMP guidelines where applicable to support our customers in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from strong bases, oxidizing agents, and sources of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.