Description

4-Amino-7-(2-C-Methyl-β-D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxamide is a high-purity nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel antiviral and anticancer therapeutics, particularly in the development of nucleoside-based prodrugs. It is essential for research institutions and pharmaceutical companies engaged in the discovery of next-generation treatments targeting viral infections and oncology.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analog antiviral drugs and anticancer agents.
• Antiviral Drug Research: Used in the R&D of therapeutics targeting viruses such as hepatitis C (HCV) and other RNA viruses.
• Oncology Research: Serves as a precursor in the development of chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Prodrug Development: Critical for creating modified nucleoside prodrugs designed for improved bioavailability and targeted delivery.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical manufacturing.

Basic Information

Product Name	4-Amino-7-(2-C-Methyl-β-D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxamide
CAS No.	139209-26-0
Molecular Formula	C13H17N5O5
Molecular Weight	323.31 g/mol
Synonyms	2'-C-Methyl-7-deaza-adenosine; 2'-C-Methyl-7-deazaadenosine; 4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-methyloxolan-2-yl]-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide; 2'-Methyl-7-deaza-adenosine; 2'-C-Methyl-7-deazaadenosine (intermediate for PSI-6130); 7-Deaza-2'-C-methyladenosine; RO-2433; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4-Amino-7-(2-C-Methyl-β-D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxamide is manufactured under strict quality control protocols suitable for pharmaceutical research. We provide comprehensive analytical data to support your development work. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request, ensuring traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC, Area %)	≥98.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.