Description

Naphtho[2,3-D][1,3]Dioxole-2-Carbonyl Chloride CAS NO 139053-68-2 is a specialized aromatic acid chloride derivative, serving as a critical high-purity synthetic intermediate for constructing complex organic frameworks. Its value lies in its high reactivity, enabling efficient formation of amide and ester bonds under mild conditions, which is essential for precise molecular assembly. This compound is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, contributing to crop protection solutions.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or optical properties.
• Material Science Research: Employed in creating organic semiconductors, liquid crystals, and other functional materials for electronic applications.
• Chemical Biology Probes: Utilized to synthesize labeled compounds or activity-based probes for biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical manufacturers offering bespoke synthesis services to global clients.

Basic Information

Product Name	Naphtho[2,3-D][1,3]Dioxole-2-Carbonyl Chloride
CAS No.	139053-68-2
Molecular Formula	C₁₄H₇ClO₃
Molecular Weight	258.66 g/mol
Synonyms	2-Naphtho[2,3-d][1,3]dioxole-5-carbonyl chloride; 5-Chlorocarbonylnaphtho[2,3-d][1,3]dioxole; Naphtho[2,3-d]-1,3-dioxole-2-carbonyl chloride; 1,3-Dioxolo[4,5-j]phenanthridine-9-carbonyl chloride; 1,3-Benzodioxolo[5,6-c]phenanthridine-11-carbonyl chloride; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of Naphtho[2,3-D][1,3]Dioxole-2-Carbonyl Chloride is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. Our standard grade meets high-purity specifications suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.