Description

1,2,4-Oxadiazolidine-2-Carbonyl Chloride, 4-Methyl-3,5-Dioxo- (9Ci) CAS NO 139037-69-7 is a specialized heterocyclic building block featuring a reactive carbonyl chloride group. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for constructing novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those containing the 1,2,4-oxadiazolidine heterocycle.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with potentially enhanced activity and selectivity.
• Peptide Mimetics & Conjugation: The reactive acid chloride moiety enables efficient coupling reactions for creating peptide-like structures or conjugating payloads in bioconjugation chemistry.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialized polymers with unique thermal or chemical properties.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme function and biological pathways in R&D settings.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Detail
Product Name	1,2,4-Oxadiazolidine-2-Carbonyl Chloride, 4-Methyl-3,5-Dioxo- (9Ci)
CAS No.	139037-69-7
Molecular Formula	C4H3ClN2O3
Molecular Weight	162.53 g/mol
Synonyms	4-Methyl-3,5-dioxo-1,2,4-oxadiazolidine-2-carbonyl chloride; 2-(Chlorocarbonyl)-4-methyl-1,2,4-oxadiazolidine-3,5-dione; 4-Methyl-3,5-dioxo-1,2,4-oxadiazolidine-2-carboxylic acid chloride; 1,2,4-Oxadiazolidine-2-carbonyl chloride, 4-methyl-3,5-dioxo-; 4-Methyl-1,2,4-oxadiazolidine-3,5-dione-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 1,2,4-Oxadiazolidine-2-Carbonyl Chloride, 4-Methyl-3,5-Dioxo- undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. Our quality assurance protocols are designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.