Description

3-Glucosido-Chenodeoxycholic Acid is a conjugated bile acid derivative, specifically the glucosidic ester of chenodeoxycholic acid. This specialized biochemical is a critical intermediate and reference standard in pharmaceutical research and development, particularly for studying bile acid metabolism and transport. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent sectors who require high-purity biochemicals for metabolic studies, drug discovery, and analytical method development.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate and reference standard in the synthesis and study of novel therapeutic agents targeting bile acid pathways, such as treatments for cholestatic liver diseases.
• Metabolic Pathway Analysis: Used as a biochemical tool to investigate the metabolism, conjugation, and enterohepatic circulation of bile acids in in vitro and in vivo models.
• Diagnostic Reagent Manufacturing: Employed in the production of calibration standards and reagents for clinical diagnostic kits that measure bile acid profiles, aiding in the diagnosis of liver and gastrointestinal disorders.
• Enzymology Studies: Acts as a specific substrate for studying the activity of enzymes involved in bile acid conjugation and modification, such as bile acid-CoA:amino acid N-acyltransferase (BAAT) and related glucosyltransferases.
• Cell Biology & Toxicology: Utilized in cell culture studies to examine the effects of conjugated bile acids on cell signaling, apoptosis, and membrane integrity in hepatocytes and other cell types.

Basic Information

Product Name	3-Glucosido-Chenodeoxycholic Acid
CAS No.	139026-50-9
Molecular Formula	C30H50O9
Molecular Weight	554.72 g/mol
Synonyms	Chenodeoxycholic Acid 3-Glucoside; 3β-Glucopyranosyl-3α,7α-dihydroxy-5β-cholan-24-oic Acid; 3-O-β-D-Glucopyranosylchenodeoxycholic Acid; CDCAGlc; Chenodeoxycholylglucoside; 3-Glucosylchenodeoxycholic Acid; Glyco-3-glucosido-chenodeoxycholic Acid (common naming variant)
EINECS	Contact for details

Quality Control

Our 3-Glucosido-Chenodeoxycholic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We support compliance with relevant guidelines for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the material may be stored at 2-8°C. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. The compound is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.