Description

4-Pregnen-17A, 20B-Diol-3-One-20-Sulfate CAS NO 138949-80-1 is a high-purity steroid sulfate derivative, serving as a critical advanced intermediate in pharmaceutical synthesis. This compound is valued for its specific stereochemistry and functional groups, which are essential for the development of specialized steroid-based therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel hormonal agents and metabolic regulators.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies and metabolic pathway research.
• Hormone Analog Development: Serves as a precursor for the development of novel corticosteroids or other hormonal analogs with modified activity.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of target steroid molecules.
• Academic Research: Utilized in university and institutional labs for studying steroid chemistry, sulfation pathways, and receptor interactions.

Basic Information

Product Name	4-Pregnen-17A, 20B-Diol-3-One-20-Sulfate
CAS No.	138949-80-1
Molecular Formula	C21H32O6S
Molecular Weight	412.54 g/mol
Synonyms	Pregnenolone-20-sulfate; 20β-Hydroxypregn-4-en-3-one 20-sulfate; 17α,20β-Dihydroxypregn-4-en-3-one 20-sulfate; 4-Pregnene-17α,20β-diol-3-one 20-sulfate; 20-Sulfoxy-17α,20β-dihydroxypregn-4-en-3-one; NSC 113986; Pregnenolone sulfate derivative
EINECS	Contact for details

Quality Control

Our 4-Pregnen-17A, 20B-Diol-3-One-20-Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.