Description

Pentafluorophenyl Diphenylphosphinate is a specialized organophosphorus compound featuring a pentafluorophenyl group, making it a valuable reagent in advanced synthetic chemistry. Its primary value lies in its role as a highly effective coupling agent and phosphorylating agent, particularly useful for activating carboxylic acids. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for complex molecule synthesis.

Application

• Peptide Coupling Reagent: Used as an efficient activator for amide bond formation in solid-phase and solution-phase peptide synthesis.
• Phosphorylation Agent: Employed in the synthesis of phosphate esters and other organophosphorus compounds for pharmaceutical and material science applications.
• Intermediate for Catalysts & Ligands: Serves as a key precursor in the preparation of specialized phosphine ligands and metal catalysts used in cross-coupling reactions.
• Polymer Chemistry: Utilized in the modification and functionalization of polymers to introduce specific phosphinate groups, altering material properties.
• Agrochemical Synthesis: Acts as a building block in the development of novel active ingredients, such as herbicides and insecticides.
• Chemical Biology Probes: Applied in the synthesis of labeled compounds and probes for studying biological mechanisms and enzyme activity.

Basic Information

Product Name	Pentafluorophenyl Diphenylphosphinate
CAS No.	138687-69-1
Molecular Formula	C18H10F5O2P
Molecular Weight	384.24 g/mol
Synonyms	Diphenyl(pentafluorophenyl)phosphinate; Pentafluorophenyl Diphenylphosphinate; PFPDP; (Pentafluorophenoxy)diphenylphosphine oxide; NSC 405124; Phosphinic acid, P,P-diphenyl-, 2,3,4,5,6-pentafluorophenyl ester
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl Diphenylphosphinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.