Description

6'-C-Methylneplanocin A is a synthetic nucleoside analog and a potent inhibitor of S-adenosylhomocysteine hydrolase (SAHase). This compound is a key research tool for studying epigenetic regulation, viral replication, and cellular methylation processes. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions engaged in antiviral drug discovery, oncology research, and the development of novel therapeutics targeting methylation pathways.

Application

• Antiviral Research: Investigated for its activity against a range of viruses, including poxviruses and other DNA viruses, by disrupting viral mRNA cap methylation.
• Oncology & Cancer Research: Serves as a biochemical probe to study the role of methylation in cancer cell proliferation and as a potential lead compound for anticancer agents.
• Epigenetics Studies: Used to modulate cellular methylation status by inhibiting SAHase, thereby affecting DNA and histone methylation patterns.
• Biochemical Assay Development: Employed as a standard or inhibitor in enzymatic assays for SAHase activity screening.
• Medicinal Chemistry & Drug Discovery: Acts as a sophisticated building block or reference compound for the synthesis and evaluation of novel nucleoside-based therapeutics.
• Academic Research: Fundamental research in virology, parasitology, and cellular biochemistry to understand methylation-dependent biological pathways.

Basic Information

Product Name	6'-C-Methylneplanocin A
CAS No.	138571-54-7
Molecular Formula	C13H17N5O4
Molecular Weight	307.31 g/mol
Synonyms	6'-C-Methylneplanocin A; 6'-Methylneplanocin A; (1S,2R,3S,4R)-2-(6-Amino-9H-purin-9-yl)-3,4-dihydroxy-1-methylcyclopentanecarbonitrile; 9-[(1S,2R,3S,4R)-2-Cyano-3,4-dihydroxy-1-methylcyclopentyl]adenine; 6'-Methylaristeromycin; SAH Hydrolase Inhibitor; Adenosine, 9-[2-cyano-3,4-dihydroxy-1-methylcyclopentyl]-; 6'-C-Me-Npc A
EINECS	Contact for details

Quality Control

Our 6'-C-Methylneplanocin A is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Identity and purity are confirmed by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each batch to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.