Description

R-(+)-Lansoprazole is the pharmacologically active enantiomer of the proton pump inhibitor lansoprazole, offering superior specificity and potency for targeted therapeutic development. This high-purity chiral intermediate is critical for manufacturers aiming to produce enantiomerically pure pharmaceuticals with enhanced efficacy and reduced side-effect profiles. It is primarily required by advanced pharmaceutical R&D laboratories and API producers focused on next-generation gastrointestinal treatments and chiral switch applications.

Application

• Key chiral building block for the synthesis of enantiomerically pure dexlansoprazole API.
• Active pharmaceutical ingredient (API) intermediate in advanced proton pump inhibitor (PPI) formulations.
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Research chemical for studying the mechanism of action of specific H+/K+ ATPase inhibition.
• Starting material for the development of novel gastroesophageal reflux disease (GERD) and ulcer medications.
• Used in preclinical and clinical studies to establish pharmacokinetic and pharmacodynamic profiles.

Basic Information

Item	Detail
Product Name	R-(+)-Lansoprazole
CAS No.	138530-94-6
Molecular Formula	C16H14F3N3O2S
Molecular Weight	369.36 g/mol
Synonyms	(R)-(+)-Lansoprazole; Dexlansoprazole Related Compound A; (R)-Lansoprazole; (+)-Lansoprazole; R-Lansoprazole; AG-1749 (R-form); (R)-2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole; Lansoprazole R-enantiomer
EINECS	Contact for details

Quality Control

Our R-(+)-Lansoprazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. The product is characterized and released according to comprehensive in-house specifications, which include chiral purity verification. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Chiral Purity (Enantiomeric Excess)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.