Description

Carbamic Acid, (3-Amino-2-Fluoropropoxy)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized tert-butyl carbamate-protected amino alcohol derivative featuring a fluorine substituent. This compound matters as a high-value pharmaceutical intermediate and building block for medicinal chemistry, enabling the synthesis of complex molecules with enhanced metabolic stability and bioavailability. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Protease Inhibitor Synthesis: Used in the research and development of protease inhibitors, where the fluorine atom and protected amine are critical for binding affinity and selectivity.
• Peptidomimetic Chemistry: Serves as a fluorine-containing scaffold for creating peptidomimetics and modified peptides to improve drug-like properties.
• Agrochemical Research: Employed as an intermediate in developing new generation herbicides, fungicides, and pesticides with optimized efficacy and environmental profiles.
• Ligand and Catalyst Development: Utilized in organometallic chemistry for preparing novel chiral ligands and catalysts for asymmetric synthesis.
• Material Science Precursor: Acts as a monomer or functionalization agent in the synthesis of specialty polymers and advanced functional materials.

Basic Information

Product Name	Carbamic Acid, (3-Amino-2-Fluoropropoxy)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	138142-80-0
Molecular Formula	C8H17FN2O3
Molecular Weight	208.23 g/mol
Synonyms	tert-Butyl N-(3-amino-2-fluoropropoxy)carbamate; 1,1-Dimethylethyl N-[3-amino-2-fluoropropoxy]carbamate; N-(tert-Butoxycarbonyl)-3-amino-2-fluoropropoxyamine; 2-Fluoro-3-[(tert-butoxycarbonyl)amino]propan-1-ol derivative; Boc-3-Amino-2-fluoropropanol carbamate; 138142-80-0; (3-Amino-2-fluoropropoxy)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (3-Amino-2-Fluoropropoxy)-, 1,1-Dimethylethyl Ester (9Ci) is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay, impurity profile, and chiral purity where applicable. Our quality commitment supports cGMP and ISO standards for pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.