Description

Pregnane-3,7,17,20-Tetrol is a high-purity steroid derivative and a key intermediate in the synthesis of complex bioactive molecules. This compound is valued for its defined stereochemistry and functional group array, which makes it a versatile building block for pharmaceutical research and development. It is primarily utilized by research institutions and manufacturers in the life sciences sector for the development of novel therapeutic agents and reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of steroidal drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or starting material in metabolic pathway studies and enzyme interaction research.
• Hormone Analog Development: Serves as a core scaffold for the design and synthesis of novel hormone analogs and receptor modulators.
• Analytical Standard: Employed as a high-purity calibrant or standard in chromatographic (HPLC, GC) and spectroscopic analysis for quality control laboratories.

Basic Information

Product Name	Pregnane-3,7,17,20-Tetrol
CAS No.	137767-50-1
Molecular Formula	C21H36O4
Molecular Weight	352.51 g/mol
Synonyms	3,7,17,20-Tetrahydroxypregnane; Pregnane-3α,7α,17α,20β-tetrol; 5β-Pregnane-3α,7α,17α,20β-tetrol; 3,7,17,20-Pregnanetetrol; 20β-Hydroxy-5β-pregnane-3α,7α,17α-triol; 5β-Pregnan-3α,7α,17α,20β-tetrol; (3α,5β,7α,17α,20β)-Pregnane-3,7,17,20-tetrol
EINECS	Contact for details

Quality Control

Our Pregnane-3,7,17,20-Tetrol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, verified by advanced analytical techniques including HPLC and NMR. We support compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.