Description

5-(3-(4-Azidosalicylamide)Allyluridine)- 5'-Diphosphoglucose is a specialized nucleotide sugar derivative designed for advanced biochemical research and development. This compound is a critical tool for the site-specific labeling and cross-linking of biomolecules, particularly in the study of carbohydrate-protein interactions and glycobiology. It is essential for researchers and manufacturers in the fields of pharmaceutical development, proteomics, and diagnostic assay design who require high-purity, functionalized biochemical building blocks.

Application

• Glycobiology Research: As a functionalized UDP-glucose analog for enzymatic glycosylation studies and metabolic labeling of glycans.
• Photoaffinity Labeling: The azido group enables UV-induced cross-linking for identifying and characterizing carbohydrate-binding proteins and enzymes.
• Bioconjugation & Probe Development: Serves as a key intermediate for synthesizing fluorescent or affinity-tagged nucleotide sugar probes.
• Enzyme Mechanism Studies: Used to investigate the active sites and catalytic mechanisms of glycosyltransferases and related enzymes.
• Diagnostic Reagent Synthesis: A precursor for developing sensitive diagnostic assays targeting specific carbohydrate epitopes.
• Chemical Biology Tool Development: Enables the creation of tools for manipulating and tracking glycosylation pathways in live cells.

Basic Information

Product Name	5-(3-(4-Azidosalicylamide)Allyluridine)- 5'-Diphosphoglucose
CAS No.	137731-71-6
Molecular Formula	C₂₅H₃₁N₆O₁₇P₂
Molecular Weight	773.50 g/mol
Synonyms	5-[3-[(4-Azido-2-hydroxybenzoyl)amino]prop-2-en-1-yl]uridine 5'-(trihydrogen diphosphate) β-D-glucopyranosyl ester; UDP-5-[3-[(4-Azidosalicylamido)allyl]]uridine; Azido-Sal-allyl-UDP-Glucose; 5-(3-(4-Azidosalicylamido)allyl)uridine diphosphate glucose; Photoactivatable UDP-Glucose Derivative; 5-(N-(4-Azido-2-hydroxybenzoyl)-3-aminoprop-1-enyl)uridine 5'-diphosphoglucose
EINECS	Contact for details

Quality Control

Our production of this high-value biochemical adheres to stringent quality protocols. Every batch is characterized and purified to ensure high chemical and isomeric purity, critical for reproducible research outcomes. Comprehensive analysis via HPLC, NMR, and mass spectrometry is performed to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. Due to its hygroscopic and light-sensitive nature, the product should be handled under inert atmosphere or in a controlled, dry environment when aliquoting. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.