Description

3-Deaza-9-(3-Hydroxy-2-Phosphonylmethoxypropyl)Adenine is a chemically modified nucleoside analogue designed for advanced biochemical and pharmaceutical research. This compound is valued for its role as a potent and selective inhibitor of specific cellular enzymes, making it a critical tool for investigating nucleotide metabolism and signaling pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in antiviral, anticancer, and metabolic disease research, as well as by fine chemical suppliers serving these sectors.

Application

• Biochemical Research: Used as a key inhibitor to study S-adenosylhomocysteine hydrolase (SAH hydrolase) and related enzymatic pathways.
• Antiviral Agent Development: Investigated for its potential activity against a broad spectrum of viruses due to its mechanism of interfering with viral methylation processes.
• Oncology Research: Serves as a tool compound in cancer research to explore the role of methylation in tumor cell proliferation and epigenetics.
• Pharmaceutical Intermediates: Acts as a sophisticated building block for the synthesis of novel nucleoside-based therapeutic candidates.
• Enzyme Inhibition Studies: Employed in high-throughput screening (HTS) and mechanistic studies to identify and validate new drug targets.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3-Deaza-9-(3-Hydroxy-2-Phosphonylmethoxypropyl)Adenine
CAS No.	137427-72-6
Molecular Formula	C13H19N5O6P
Molecular Weight	372.30 g/mol
Synonyms	3-Deazaadenosine Phosphonate Derivative; 3-Deaza-9-[3-Hydroxy-2-(phosphonomethoxy)propyl]adenine; 3-Deaza-HPMPA; MDL 28881; (S)-HPMP-3-deazaA; 9-[(2S)-3-Hydroxy-2-(phosphonomethoxy)propyl]-3-deazaadenine; 3-Deaza-(S)-HPMPA; Adenine, 9-[3-hydroxy-2-(phosphonomethoxy)propyl]-3-deaza-
EINECS	Contact for details

Quality Control

Our 3-Deaza-9-(3-Hydroxy-2-Phosphonylmethoxypropyl)Adenine is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.