Description

3-Chloro-5,6-Methylenedioxybenzothiophene-2-Carbonyl Chloride is a high-purity, reactive chemical intermediate of significant importance in advanced organic synthesis. Its value lies in its dual functional groups, making it a versatile building block for constructing complex heterocyclic frameworks. This compound is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its benzothiophene core.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the methylenedioxy and chlorinated benzothiophene structure can impart specific biological activity.
• Material Science Research: Serves as a monomer or building block for developing novel organic electronic materials, such as semiconductors or conductive polymers.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized heterocyclic dyes and pigments for high-performance applications.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) working on client-specific molecular targets.
• Academic and Industrial R&D: Fundamental building block in medicinal chemistry and synthetic methodology research for exploring new chemical spaces and reaction pathways.

Basic Information

Product Name	3-Chloro-5,6-Methylenedioxybenzothiophene-2-Carbonyl Chloride
CAS No.	137278-46-7
Molecular Formula	C10H4Cl2O3S
Molecular Weight	275.11 g/mol
Synonyms	3-Chloro-5,6-(methylenedioxy)thianaphthene-2-carbonyl chloride; 2-(Chlorocarbonyl)-3-chloro-5,6-methylenedioxybenzothiophene; 3-Chloro-5,6-methylenedioxybenzo[b]thiophene-2-carbonyl chloride; 3-Chloro-5,6-(methylenedioxy)benzo[b]thiophene-2-carbonyl chloride; 2-Carbonyl chloride-3-chloro-5,6-methylenedioxybenzothiophene
EINECS	Contact for details

Quality Control

Our 3-Chloro-5,6-Methylenedioxybenzothiophene-2-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.