Description

Acetamide, n-(2-Oxoethyl)-n-[(Trimethylsilyl)Methyl]- is a specialized organosilicon compound featuring a unique acetamide backbone modified with a trimethylsilylmethyl group. This structure makes it a valuable synthetic intermediate and building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring silicon-containing functional groups.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its specific moiety can influence biological activity.
• Organosilicon Chemistry: Acts as a versatile building block for introducing the trimethylsilylmethyl group into target molecules, facilitating further chemical transformations.
• Material Science Research: Employed in the development of specialty polymers and advanced materials with tailored surface properties.
• Cross-Coupling Reactions: Functions as a substrate or ligand precursor in metal-catalyzed coupling reactions for carbon-carbon bond formation.
• Process Chemistry: Investigated for scalable manufacturing routes of complex organic compounds in pilot plants and commercial production.

Basic Information

Item	Details
Product Name	Acetamide, n-(2-Oxoethyl)-n-[(Trimethylsilyl)Methyl]-
CAS No.	137257-85-3
Molecular Formula	C8H17NO2Si
Molecular Weight	187.31 g/mol
Synonyms	N-[(Trimethylsilyl)methyl]-N-(2-oxoethyl)acetamide; N-(2-Oxoethyl)-N-[(trimethylsilyl)methyl]acetamide; Acetamide, N-(2-oxoethyl)-N-[(trimethylsilyl)methyl]-; (Acetamido)(trimethylsilyl)methane acetaldehyde; Glycinaldehyde N-(trimethylsilylmethyl)acetamide; TMSM-acetamide acetaldehyde
EINECS	Contact for details

Quality Control

Our production of Acetamide, n-(2-Oxoethyl)-n-[(Trimethylsilyl)Methyl]- adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.