Description

Voriconazole is a broad-spectrum triazole antifungal agent, representing a critical second-generation development in antifungal therapy. Its primary value lies in its enhanced potency and spectrum of activity against severe systemic fungal infections, including those resistant to first-line treatments. This active pharmaceutical ingredient (API) is essential for pharmaceutical manufacturers developing injectable, oral, and ophthalmic formulations to treat invasive aspergillosis, candidemia, and other serious fungal diseases in immunocompromised patients.

Application

• Pharmaceutical API: Core ingredient in the manufacture of antifungal prescription medications.
• Injectable Formulations: Used in lyophilized powders or solutions for intravenous administration in hospital settings.
• Oral Solid Dosage Forms: Key component in the production of tablets and capsules for outpatient treatment.
• Ophthalmic Solutions: Utilized in eye drop formulations for the treatment of fungal keratitis.
• Research & Development: Serves as a reference standard and building block in antimicrobial and pharmacological research.
• Veterinary Pharmaceuticals: Applied in developing antifungal treatments for companion and livestock animals.

Basic Information

Product Name	Voriconazole
CAS No.	137234-71-0
Molecular Formula	C16H14N5FO
Molecular Weight	307.31 g/mol
Synonyms	UK-109,496; UK109496; (2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol; Vfend (Brand Name); 4-Pyrimidinol, 5-fluoro-4-[2R,3S)-3-(1H-1,2,4-triazol-1-yl)-2-(2,4-difluorophenyl)butyl]-; Voriconazol; Voriconazolum
EINECS	Contact for details

Quality Control

Our Voriconazole is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards including USP and EP. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and potency. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and microbiological quality is provided with every shipment, supporting regulatory submissions and supply chain integrity for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 0.5%
Related Substances (HPLC)	Total impurities: NMT 1.0% Any individual impurity: NMT 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	NMT 20 ppm
Sulfated Ash	NMT 0.1%
Microbiological Enumeration	Complies with EP/USP for non-sterile substances

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.