Description

Ent-Voriconazole is the enantiomerically pure form of the potent antifungal agent Voriconazole, representing a critical chiral building block in advanced pharmaceutical synthesis. Its high optical purity is essential for research and development into novel antifungal therapies and for studying stereospecific biological activity. This compound is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on chiral chemistry and antifungal drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of enantiomerically pure antifungal active pharmaceutical ingredients (APIs).
• Research & Development: Used in bioactivity studies to investigate the stereospecific efficacy and pharmacokinetics of antifungal compounds.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in chiral HPLC analysis.
• Process Chemistry: Integral to route scouting and optimization for the scalable production of chiral antifungal agents.
• Academic Research: A valuable tool for studies in medicinal chemistry, pharmacology, and asymmetric synthesis.

Basic Information

Product Name	Ent-Voriconazole
CAS No.	137234-63-0
Molecular Formula	C16H14F3N5O
Molecular Weight	349.31 g/mol
Synonyms	(2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol; (2R,3S)-Voriconazole; Voriconazole Enantiomer; UNII-7S6B4D4K8B; (αR,βS)-α-(2,4-Difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
EINECS	Contact for details

Quality Control

Our Ent-Voriconazole CAS NO 137234-63-0 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay by HPLC, to ensure it meets exacting standards for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.