Description

N6-(2-Hydroxyethyl)-2'-Deoxyadenosine is a modified nucleoside analog, a key building block in nucleic acid chemistry and biochemical research. This compound is valued for its role in the synthesis of oligonucleotides and as a research tool for studying DNA structure, function, and modification. It is essential for pharmaceutical R&D, academic laboratories, and biotechnology companies focused on developing novel therapeutics, diagnostic probes, and advanced molecular biology applications.

Application

• Oligonucleotide Synthesis: A critical phosphoramidite precursor for the solid-phase synthesis of modified DNA strands.
• Pharmaceutical Research: Used in the development of antisense oligonucleotides, aptamers, and other nucleic acid-based therapeutics.
• Biochemical Probes: Incorporation into DNA probes to study enzyme mechanisms, DNA-protein interactions, and epigenetic modifications.
• Diagnostic Development: Serves as a component in the design of sensitive and specific molecular diagnostic assays.
• Academic Research: A valuable reagent for fundamental studies in molecular biology, genetics, and chemical biology.
• Bioconjugation: The hydroxyethyl side chain provides a handle for further chemical modification and conjugation with other molecules.

Basic Information

Product Name	N6-(2-Hydroxyethyl)-2'-Deoxyadenosine
CAS No.	137058-94-7
Molecular Formula	C12H17N5O4
Molecular Weight	295.29 g/mol
Synonyms	N6-(2-Hydroxyethyl)deoxyadenosine; 2'-Deoxy-N6-(2-hydroxyethyl)adenosine; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-N6-(2-hydroxyethyl)adenine; N6-Hydroxyethyl-2'-deoxyadenosine; dA(N6-HE); HE-dA; N6-(2-Hydroxyethyl)adenine deoxyriboside
EINECS	Contact for details

Quality Control

Our N6-(2-Hydroxyethyl)-2'-Deoxyadenosine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.