Description

6-Methoxy-9-[2-O,5-o-Bis(1-Oxopentyl)-β-D-Arabinofuranosyl]-9H-Purine is a high-purity, modified nucleoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel antiviral and anticancer agents, where precise molecular structure is paramount for biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating next-generation therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside analog drugs targeting viral infections and oncology.
• Antiviral Drug Research: Used in the development of experimental therapeutics against DNA and RNA viruses.
• Anticancer Agent Development: Serves as a scaffold for creating compounds that interfere with cancer cell proliferation.
• Biochemical Research: Employed in studies of enzyme mechanisms, particularly those involving nucleoside kinases and polymerases.
• Process Chemistry & Scale-Up: Used in optimizing synthetic routes for the commercial production of active pharmaceutical ingredients (APIs).
• Labeled Compound Synthesis: A starting material for preparing isotopically labeled (e.g., C13, N15) versions for metabolic and pharmacokinetic studies.

Basic Information

Product Name	6-Methoxy-9-[2-O,5-o-Bis(1-Oxopentyl)-β-D-Arabinofuranosyl]-9H-Purine
CAS No.	137057-69-3
Molecular Formula	C22H30N4O8
Molecular Weight	478.50 g/mol
Synonyms	6-Methoxy-9-[2,5-di-O-valeryl-β-D-arabinofuranosyl]purine; 9-(2,5-Di-O-pentanoyl-β-D-arabinofuranosyl)-6-methoxypurine; 6-Methoxy-9-(2,5-di-O-valeryl-β-D-arabinofuranosyl)-9H-purine; 2',5'-Di-O-valeryl-6-methoxy-9-β-D-arabinofuranosylpurine; Valeryl Ester of 6-Methoxy-9-β-D-arabinofuranosylpurine; Modified Arabinofuranosyl Purine Derivative; Nucleoside Valerate Ester Intermediate
EINECS	Contact for details

Quality Control

Our 6-Methoxy-9-[2-O,5-o-Bis(1-Oxopentyl)-β-D-Arabinofuranosyl]-9H-Purine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities to meet the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.