Description

6-Methoxy-9-[2-O,3-O,5-o-Tris(1-Oxopropyl)-β-D-Arabinofuranosyl]-9H-Purine is a sophisticated nucleoside analog derivative, representing a key building block in advanced pharmaceutical research and development. Its value lies in its role as a crucial intermediate for synthesizing novel antiviral and anticancer agents, particularly within the field of nucleoside chemistry. This high-purity compound is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Primary use as a critical precursor in the synthesis of novel nucleoside-based antiviral drugs.
• Anticancer Agent Research: Serves as a key scaffold for developing purine nucleoside analogs with potential antitumor activity.
• Biochemical Research: Used in enzymatic studies and as a substrate analog to investigate nucleoside metabolism and related pathways.
• Prodrug Development: The tris-O-propionyl protecting groups make it a valuable intermediate for creating prodrug forms of active nucleosides to enhance bioavailability.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized, high-value chemical entities.

Basic Information

Product Name	6-Methoxy-9-[2-O,3-O,5-o-Tris(1-Oxopropyl)-β-D-Arabinofuranosyl]-9H-Purine
CAS No.	137057-42-2
Molecular Formula	C22H30N4O9
Molecular Weight	494.50 g/mol
Synonyms	9-(2,3,5-Tri-O-propionyl-β-D-arabinofuranosyl)-6-methoxypurine; 6-Methoxy-9-(2,3,5-tri-O-propionyl-β-D-arabinofuranosyl)purine; 6-Methoxy-9-(tri-O-propionyl-β-D-arabinofuranosyl)purine; 6-Methoxypurine arabinoside tripropionate; Ara-6-Methoxypurine tripropionate; β-D-Arabinofuranoside, 6-methoxy-9H-purin-9-yl, 2,3,5-tripropanoate; 137057-42-2 (CAS)
EINECS	Contact for details

Quality Control

Our 6-Methoxy-9-[2-O,3-O,5-o-Tris(1-Oxopropyl)-β-D-Arabinofuranosyl]-9H-Purine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The compound is moisture-sensitive (hygroscopic); ensure the container is sealed under inert atmosphere after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.