Description

Butanoyl Chloride, 4-Amino-, Hydrochloride is a specialized organic intermediate featuring both an amino group and an acid chloride functionality. This unique bifunctional structure makes it a valuable building block for the synthesis of more complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing peptide mimetics, amide linkages, and other targeted compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring amide bond formation.
• Peptidomimetic Synthesis: Used to create peptide analogs and mimetics for drug discovery programs targeting various diseases.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Employed in the production of specialty polyamides and other functional polymers.
• Bioconjugation Reagent: Facilitates the coupling of molecules to proteins, antibodies, or other biomolecules for diagnostic and therapeutic applications.
• Organic Synthesis: A versatile reagent for introducing the 4-aminobutanoyl moiety into complex molecular architectures in academic and industrial research.

Basic Information

Product Name	Butanoyl Chloride, 4-Amino-, Hydrochloride
CAS No.	137048-10-3
Molecular Formula	C₄H₈ClNO•HCl
Molecular Weight	158.03 g/mol (Free base: 121.56 g/mol)
Synonyms	4-Aminobutanoyl Chloride Hydrochloride; γ-Aminobutyryl Chloride Hydrochloride; 4-Aminobutyryl Chloride Hydrochloride; GABA Chloride Hydrochloride; Butyryl Chloride, 4-Amino-, Hydrochloride; 4-Aminobutanoic Acid Chloride Hydrochloride; NSC 401148 (Hydrochloride)
EINECS	Contact for details

Quality Control

Our Butanoyl Chloride, 4-Amino-, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), assay (HPLC/Titration), and impurity profiling, to ensure it meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in polar organic solvents (e.g., DMF, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.