Description

4-Isoxazolecarbonyl Chloride, 5-Phenyl- (9Ci) is a specialized heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its high reactivity, enabling efficient introduction of the 5-phenylisoxazole moiety into complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the bioactive isoxazole scaffold.
• Material Science Research: Serves as a monomer or cross-linking agent in the creation of specialized polymers with unique thermal or optical properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of activity-based probes.
• Academic & R&D Laboratories: Fundamental reagent for methodological studies in heterocyclic and medicinal chemistry.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	4-Isoxazolecarbonyl Chloride, 5-Phenyl- (9Ci)
CAS No.	136995-29-4
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	5-Phenylisoxazole-4-carbonyl chloride; 5-Phenyl-4-isoxazolecarbonyl chloride; 4-Carboxy-5-phenylisoxazole chloride; 5-Phenyl-1,2-oxazole-4-carbonyl chloride; Isoxazole-4-carbonyl chloride, 5-phenyl-; 136995-29-4; 5-Phenyl-isoxazole-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of 4-Isoxazolecarbonyl Chloride, 5-Phenyl- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We operate under a quality management system and can support development projects requiring GMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.