Description

2-Chloro-3-quinolinecarbonyl chloride is a versatile and highly reactive chemical intermediate belonging to the quinoline family. This compound matters for its crucial role as a key building block in the synthesis of more complex heterocyclic molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and specialty fine chemicals. Its reactive acid chloride group makes it an essential precursor for amide and ester bond formation.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides with quinoline core structures.
• Material Science Research: Serves as a precursor for creating functionalized polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of activity-based probes and molecular tags for studying biological systems.
• Dye & Pigment Industry: Intermediate for the production of specialized quinoline-derived colorants and fluorescent markers.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-3-quinolinecarbonyl chloride
CAS No.	136812-19-6
Molecular Formula	C10H5Cl2NO
Molecular Weight	226.06 g/mol
Synonyms	2-Chloroquinoline-3-carbonyl chloride; 3-Quinolinecarbonyl chloride, 2-chloro-; 2-Chloro-3-quinolinecarboxylic acid chloride; 2-Chloroquinoline-3-carboxylic acid chloride; 2-Chloro-quinoline-3-carbonyl chloride; Quinoline-3-carbonyl chloride, 2-chloro-; 136812-19-6
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-quinolinecarbonyl chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity determination, to meet the specifications required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.