Description

Adenosine 2'-Phosphate 5'-Methylenephosphosulfate is a specialized nucleotide analog and a key biochemical reagent. This compound is critical for research and development in enzymology and molecular biology, serving as a substrate or inhibitor for various enzymes involved in nucleotide metabolism. It is primarily utilized by pharmaceutical researchers, diagnostic kit manufacturers, and academic institutions focused on signal transduction pathways and kinase/phosphatase studies.

Application

• Enzymology Research: Acts as a substrate or competitive inhibitor for studies involving sulfotransferases, kinases, and other nucleotide-processing enzymes.
• Biochemical Assay Development: Used in the formulation of high-throughput screening (HTS) assays for drug discovery targeting nucleotide-binding proteins.
• Diagnostic Reagent Manufacturing: A key component in the production of reagents for clinical diagnostics, particularly in assays measuring cellular energy metabolism or enzyme activity.
• Signal Transduction Studies: Employed in research to elucidate adenosine-related signaling pathways and their role in cellular regulation.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
• Academic & Institutional Research: Fundamental tool for investigating the mechanism of action of novel therapeutic compounds in preclinical settings.

Basic Information

Product Name	Adenosine 2'-Phosphate 5'-Methylenephosphosulfate
CAS No.	136439-86-6
Molecular Formula	C11H16N5O12P2S
Molecular Weight	528.28 g/mol
Synonyms	Adenosine 2'-Phosphate 5'-(Methylenephosphosulfate); 2'-Phosphoadenosine 5'-(Methylenephosphosulfate); PAPS Analog; 2'-Phosphoadenosine 5'-(α,β-Methylenetriphosphate); Adenosine 2'-monophosphate 5'-(methylenephosphosulfate); 2'-P-5'-MPS-Adenosine; 2'-Phospho-5'-methylenephosphosulfate adenosine
EINECS	Contact for details

Quality Control

Every batch of Adenosine 2'-Phosphate 5'-Methylenephosphosulfate is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at -20°C. Allow the vial to equilibrate to room temperature in a dry atmosphere before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.