Description

1H-Pyrazole-5-Carbonyl Chloride, 3-Cyclopropyl-1-Methyl- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key acylating agent and reactive intermediate for constructing complex molecular architectures, particularly in the pharmaceutical sector. It is primarily needed by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used as a key building block for developing new-generation herbicides and fungicides with improved efficacy and selectivity.
• Chemical Biology Probe Development: Employed in the creation of activity-based probes and molecular tools for studying enzyme function and biological pathways.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers with unique thermal or optical properties.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	1H-Pyrazole-5-Carbonyl Chloride, 3-Cyclopropyl-1-Methyl- (9Ci)
CAS No.	136283-92-6
Molecular Formula	C8H9ClN2O
Molecular Weight	184.62 g/mol
Synonyms	3-Cyclopropyl-1-methyl-1H-pyrazole-5-carbonyl chloride; 3-Cyclopropyl-1-methylpyrazole-5-carbonyl chloride; 1-Methyl-3-cyclopropyl-1H-pyrazole-5-carbonyl chloride; 5-Carbonyl chloride-3-cyclopropyl-1-methylpyrazole; Cyclopropanepyrazolecarbonyl chloride derivative; 3-Cyclopropyl-1-methyl-1H-pyrazole-5-carboxylic acid chloride; 1-Methyl-3-cyclopropylpyrazole-5-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-5-Carbonyl Chloride, 3-Cyclopropyl-1-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.