Description

2-Methyl-Imidazo[1,2-A]Pyridin-3-Carbonyl Chloride is a high-value, reactive organic intermediate essential for advanced chemical synthesis. Its core value lies in its role as a versatile acylating and building block agent, enabling the construction of complex heterocyclic scaffolds. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides with specific biological activity.
• Material Science Research: Serves as a precursor for creating functional organic molecules used in organic light-emitting diodes (OLEDs) and other electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical companies offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	2-Methyl-Imidazo[1,2-A]Pyridin-3-Carbonyl Chloride
CAS No.	135854-51-2
Molecular Formula	C9H7ClN2O
Molecular Weight	194.62 g/mol
Synonyms	2-Methylimidazo[1,2-a]pyridine-3-carbonyl chloride; 3-Carbonyl chloride-2-methylimidazo[1,2-a]pyridine; 2-Methyl-3-carbamoylchlorideimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-3-carbonyl chloride, 2-methyl-; 135854-51-2; 2-Methylimidazo[1,2-a]pyridine-3-carbonyl chloride; 2-Methyl-3-(chlorocarbonyl)imidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 2-Methyl-Imidazo[1,2-A]Pyridin-3-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to support development work under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Solubility	Soluble in common organic solvents (DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.