Description

2'-Deoxy-5-Iodouridine 5'-(4-Methoxybenzoate) is a modified nucleoside derivative, a key intermediate in the synthesis of complex antiviral and anticancer compounds. Its precise chemical structure, identified by CAS NO 135600-74-7, provides a versatile scaffold for pharmaceutical research and development. This high-purity building block is essential for medicinal chemists and researchers in the pharmaceutical and biotechnology industries focused on nucleoside-based therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop targeted therapeutic agents.
• Biochemical Probes: Serves as a substrate or inhibitor in enzymatic studies related to DNA synthesis and repair.
• Antiviral Drug Development: A precursor in the research pipeline for compounds targeting viral polymerases.
• Academic & Institutional Research: Utilized in university and government labs for fundamental studies in nucleic acid chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clients.

Basic Information

Product Name	2'-Deoxy-5-Iodouridine 5'-(4-Methoxybenzoate)
CAS No.	135600-74-7
Molecular Formula	C17H17IN2O7
Molecular Weight	488.23 g/mol
Synonyms	5-Iodo-2'-deoxyuridine 5'-(4-methoxybenzoate); 5-Iododeoxyuridine 5'-p-methoxybenzoate; 5-Iodo-2'-deoxyuridine 5'-mono(p-methoxybenzoate); IDU 5'-(4-Methoxybenzoate); 2'-Deoxy-5-iodouridine 5'-(p-methoxybenzoate); 5-Iodo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione 5'-(4-methoxybenzoate)
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-5-Iodouridine 5'-(4-Methoxybenzoate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.