Description

6-Chloropurine -9-β-D-(2'-Deoxy-2'-Fluoro)Arabino-Riboside is a high-purity nucleoside analog building block of significant importance in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel antiviral and anticancer agents, particularly within the field of nucleoside chemistry. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the development of novel therapeutic agents targeting viral polymerases.
• Oncology Research: Serves as a building block for creating potential chemotherapeutic compounds.
• Biochemical Research: Employed in studies of enzyme mechanisms, particularly those involving nucleoside kinases and polymerases.
• Pro-drug Development: Utilized in the design and synthesis of nucleoside-based pro-drugs to enhance bioavailability.
• Labeled Compound Synthesis: Acts as a starting material for the preparation of isotopically labeled compounds for metabolic and pharmacokinetic studies.

Basic Information

Product Name	6-Chloropurine -9-β-D-(2'-Deoxy-2'-Fluoro)Arabino-Riboside
CAS No.	135473-21-1
Molecular Formula	C10H11ClFN4O3
Molecular Weight	289.67 g/mol
Synonyms	6-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)purine; 2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl-6-chloropurine; 6-Chloro-9-β-D-(2-deoxy-2-fluoroarabinofuranosyl)purine; 6-Chloropurine 2'-deoxy-2'-fluoro-β-D-arabinofuranoside; 6-Cl-Purine-FMAU precursor; 2'-F-ara-6-Cl-Purine; 6-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine
EINECS	Contact for details

Quality Control

Our 6-Chloropurine -9-β-D-(2'-Deoxy-2'-Fluoro)Arabino-Riboside is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.