Description

3-Isoxazolecarbonyl Chloride, 5-(Dichloromethyl)- (9Ci) is a specialized heterocyclic acid chloride building block used in advanced organic synthesis. This compound is valued for its high reactivity, enabling the efficient introduction of the 5-(dichloromethyl)isoxazole moiety into target molecules. It is primarily required by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, particularly in medicinal chemistry research targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and fungicides, leveraging its reactive functional groups.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial R&D labs for constructing complex heterocyclic frameworks.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or functional materials requiring specific isoxazole-based monomers.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Item	Detail
Product Name	3-Isoxazolecarbonyl Chloride, 5-(Dichloromethyl)- (9Ci)
CAS No.	135335-77-2
Molecular Formula	C5H2Cl3NO2
Molecular Weight	214.43 g/mol
Synonyms	5-(Dichloromethyl)isoxazole-3-carbonyl chloride; 5-(Dichloromethyl)-1,2-oxazole-3-carbonyl chloride; 5-(Dichloromethyl)-3-isoxazolecarbonyl chloride; 3-Carbonylchloride-5-dichloromethylisoxazole; 135335-77-2; 5-(Dichloromethyl)isoxazole-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of 3-Isoxazolecarbonyl Chloride, 5-(Dichloromethyl)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.