Description

1,1-Dioxobenzo[B]Thiophen-2-Ylmethyl Chloroformate is a specialized chemical building block primarily used as a key intermediate in organic synthesis. Its value lies in its reactivity as a chloroformate ester, enabling the efficient introduction of the 1,1-dioxobenzo[b]thiophen-2-ylmethyl protecting or functional group. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of complex molecules and active ingredients.

Application

• Pharmaceutical Intermediate: A critical reagent in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides and herbicides.
• Peptide Chemistry: Can serve as a protecting group reagent for specific functionalities during peptide synthesis.
• Material Science Research: Employed in the creation of specialty polymers and functional organic materials.
• Chemical Derivatization: Useful for modifying molecules to alter their solubility, stability, or analytical properties.

Basic Information

Product Name	1,1-Dioxobenzo[B]Thiophen-2-Ylmethyl Chloroformate
CAS No.	135204-19-2
Molecular Formula	C10H7ClO5S
Molecular Weight	274.68 g/mol
Synonyms	2-(Chlorocarbonyloxymethyl)-1,1-dioxobenzo[b]thiophene; Benzo[b]thiophene-2-methanol, 1,1-dioxide, chloroformate; 1,1-Dioxobenzo[b]thiophen-2-ylmethyl chloroformate; 2-(Chloroformyloxymethyl)-1,1-dioxo-1-benzothiophene; 1,1-Dioxo-1-benzothiophen-2-ylmethyl chloroformate; BT-Sulfone Chloroformate
EINECS	Contact for details

Quality Control

Our 1,1-Dioxobenzo[B]Thiophen-2-Ylmethyl Chloroformate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC and NMR, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.