Description

Pentafluorophenyl Chlorothionoformate is a specialized organofluorine reagent featuring a highly reactive chlorothionoformate group attached to a pentafluorophenyl ring. This compound is valued for its role as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily used by R&D chemists and process development scientists in fine chemical synthesis, where its unique reactivity profile enables efficient derivatization and functional group transformations.

Application

• Key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and agrochemicals.
• Reagent for the preparation of thiocarbamate and dithiocarbamate derivatives.
• Building block for advanced materials science, including the functionalization of polymers and surfaces.
• Used in peptide chemistry and bioconjugation strategies as a coupling agent.
• Intermediate in the development of radiopharmaceuticals and diagnostic agents.
• Research chemical for exploring new reaction pathways in organofluorine chemistry.
• Starting material for the synthesis of ligands and catalysts used in asymmetric synthesis.

Basic Information

Product Name	Pentafluorophenyl Chlorothionoformate
CAS No.	135192-53-9
Molecular Formula	C7ClF5OS
Molecular Weight	262.59 g/mol
Synonyms	Pentafluorophenyl Chlorothioformate; Carbonochloridothioic Acid, 2,3,4,5,6-Pentafluorophenyl Ester; Chlorothioformic Acid Pentafluorophenyl Ester; Pentafluorophenyl Chlorosulfanylmethanoate; PFP-CTF; C6F5OC(S)Cl
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl Chlorothionoformate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development applications in the fine chemical and pharmaceutical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.