Description

2-Thiophenecarbonylchloride,4-(Methoxymethyl)-(9Ci) is a specialized organosulfur building block featuring a reactive acid chloride group and a methoxymethyl substituent on the thiophene ring. This compound matters as a critical intermediate for synthesizing complex molecules, enabling the introduction of the thiophene moiety into target structures. It is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the thiophene ring contributes to biological activity.
• Material Science Research: Serves as a monomer or precursor for developing conductive polymers, organic semiconductors, and specialty coatings.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and labeled compounds for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital reagent for fine chemical manufacturers offering bespoke synthesis services to clients.
• Ligand and Catalyst Development: Used to create novel ligands for metal catalysis and organocatalysts in asymmetric synthesis.

Basic Information

Product Name	2-Thiophenecarbonylchloride,4-(Methoxymethyl)-(9Ci)
CAS No.	135080-25-0
Molecular Formula	C7H7ClO2S
Molecular Weight	190.65 g/mol
Synonyms	4-(Methoxymethyl)thiophene-2-carbonyl chloride; 2-Thenoyl chloride, 4-(methoxymethyl)-; 4-Methoxymethyl-2-thiophenecarboxylic acid chloride; 4-(Methoxymethyl)thiophene-2-carboxylic acid chloride; 4-Methoxymethylthiophene-2-carbonyl chloride; 2-Thiophenecarbonyl chloride, 4-(methoxymethyl)-; 135080-25-0; 4-(Methoxymethyl)-2-thiophenecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarbonylchloride,4-(Methoxymethyl)-(9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. For custom synthesis projects, we adhere to cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.