Description

3-Isoxanthosine 5'-Phospho-2-Methylimidazole is a specialized nucleoside derivative and a key synthetic intermediate in advanced organic chemistry. This compound is of significant interest for its role in the research and development of novel pharmaceutical agents and biochemical tools. It is primarily utilized by researchers and manufacturers in the fields of medicinal chemistry, nucleotide synthesis, and life science research.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and related pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Nucleotide Chemistry: Employed in the preparation of modified nucleotides for probing nucleic acid structure and function.
• Academic & Contract Research: Essential for universities and CROs conducting cutting-edge research in chemical biology and drug discovery.

Basic Information

Product Name	3-Isoxanthosine 5'-Phospho-2-Methylimidazole
CAS No.	135078-46-5
Molecular Formula	C13H17N6O8P
Molecular Weight	416.28 g/mol
Synonyms	5'-Phospho-2-methylimidazole-3-isoxanthosine; 2-Methylimidazole-3-isoxanthosine 5'-phosphate; 3-Isoxanthosine, 5'-(dihydrogen phosphate), 2-methylimidazole derivative; Isoxanthosine 5'-phosphate 2-methylimidazole; 3-(2-Methyl-1H-imidazol-1-yl)-9H-purin-9-one 5'-(dihydrogen phosphate); 9H-Purin-9-one, 3-(2-methyl-1H-imidazol-1-yl)-, 5'-(dihydrogen phosphate); Nucleoside phosphoimidazole intermediate
EINECS	Contact for details

Quality Control

Our 3-Isoxanthosine 5'-Phospho-2-Methylimidazole is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.