Description

8-(2-Hydroxypropyl)Adenosine is a chemically modified nucleoside derivative of adenosine, featuring a hydroxypropyl group at the 8-position. This modification is significant as it can alter the compound's biological activity, solubility, and receptor binding profile compared to its parent molecule. It serves as a valuable pharmaceutical intermediate and research chemical for scientists in medicinal chemistry, biochemistry, and pharmacology.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel adenosine receptor agonists or antagonists for drug discovery programs.
• Biochemical Research: Used as a substrate or analog in enzymatic studies to investigate nucleoside metabolism and related pathways.
• Medicinal Chemistry: Serves as a precursor for the development of potential therapeutic agents targeting cardiovascular, neurological, or inflammatory conditions.
• Reference Standard: Employed as a high-purity standard in analytical laboratories for method development and quality control of related compounds.
• Life Science Reagents: Component in the formulation of specialized cell culture media or biochemical assay kits.

Basic Information

Product Name	8-(2-Hydroxypropyl)Adenosine
CAS No.	134895-33-3
Molecular Formula	C13H19N5O5
Molecular Weight	325.32 g/mol
Synonyms	8-(2-Hydroxypropyl)adenosine; Adenosine, 8-(2-hydroxypropyl)-; 8-(2-Hydroxypropyl)adenosine (CAS 134895-33-3); N6-(2-Hydroxypropyl)adenosine (related isomer); 8-HP-Ado; 8-(2-Hydroxy-1-methylethyl)adenosine; 8-(1-Hydroxypropan-2-yl)adenosine
EINECS	Contact for details

Quality Control

Our 8-(2-Hydroxypropyl)Adenosine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.