Description

o-Demethylchlorothricin is a chemically modified derivative of the chlorothricin class of natural products, a group of complex macrolide antibiotics. This compound is of significant interest in pharmaceutical research and development, particularly as a key intermediate or reference standard for novel therapeutic agents. Its primary value lies in its utility for structure-activity relationship (SAR) studies and as a building block in synthetic chemistry. Target users include research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on antibiotic development and chemical synthesis.

Application

• Pharmaceutical Research Intermediate: Serves as a crucial synthetic precursor or reference standard in the development of new antibiotic and antitumor agents.
• Structure-Activity Relationship (SAR) Studies: Used to investigate the biological activity of chlorothricin derivatives by modifying specific functional groups.
• Biochemical Research: Employed as a tool compound to study mechanisms of action involving complex macrolides and their interactions with biological targets.
• Fine Chemical Synthesis: Acts as a specialized building block for the synthesis of complex natural product analogs and novel chemical entities.
• Analytical Reference Standard: Utilized in HPLC, LC-MS, and NMR for method development, validation, and quality control of related compounds.

Basic Information

Product Name	o-Demethylchlorothricin
CAS No.	134637-04-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Demethylchlorothricin; Chlorothricin, O-demethyl-; 22-Demethylchlorothricin; Antibiotic X 14766A; Antibiotic X-14766A; NSC 339579; o-Demethyl-chlorothricin
EINECS	Contact for details

Quality Control

Our o-Demethylchlorothricin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (NMR, IR, MS) and purity assessment by HPLC to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results for purity, related substances, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider handling under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.