Description

1H-1,2,3-Triazole-4-Carbonyl Chloride, 1-Phenyl- (9Ci) is a versatile and reactive chemical building block, specifically an acyl chloride derivative of a phenyl-substituted triazole. This compound is crucial for the efficient synthesis of amides and esters, enabling the rapid introduction of the 1-phenyl-1,2,3-triazole-4-carbonyl moiety into more complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antivirals, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the triazole core offers unique biological activity.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating functional polymers with specific thermal or optical properties.
• Ligand & Catalyst Development: Employed to synthesize novel nitrogen-containing ligands for metal complexes used in catalysis.
• Bioconjugation & Probe Synthesis: Useful for labeling biomolecules (proteins, peptides) or creating fluorescent probes for biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical manufacturers offering bespoke synthesis services to clients in life sciences.

Basic Information

Product Name	1H-1,2,3-Triazole-4-Carbonyl Chloride, 1-Phenyl- (9Ci)
CAS No.	134541-91-6
Molecular Formula	C9H6ClN3O
Molecular Weight	207.62 g/mol
Synonyms	1-Phenyl-1H-1,2,3-triazole-4-carbonyl chloride; 1-Phenyl-1,2,3-triazole-4-carboxylic acid chloride; 1-Phenyl-1H-[1,2,3]triazole-4-carbonyl chloride; 4-Carbonyl chloride-1-phenyl-1,2,3-triazole; 1-Phenyl-1H-1,2,3-triazole-4-carbonyl chloride; 1-Phenyl-1,2,3-triazole-4-carboxyl chloride; 1-Phenyl-1H-1,2,3-triazole-4-carboxylic acid, chloride
EINECS	Contact for details

Quality Control

Our 1H-1,2,3-Triazole-4-Carbonyl Chloride, 1-Phenyl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.