Description

1-Cyclopropylisoguanosine is a synthetic nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a crucial building block and intermediate for the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing next-generation nucleotide-based therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside analog drugs targeting viral infections and specific cancers.
• Antiviral Drug Research: Used in the development of experimental antiviral compounds, potentially for hepatitis, herpesviruses, or other viral targets.
• Oncology Research: Serves as a scaffold for creating potential chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Tool Compound: Employed in enzymatic studies and as a probe to investigate nucleoside metabolism and related cellular pathways.
• Medicinal Chemistry: Utilized for structure-activity relationship (SAR) studies to optimize the potency and selectivity of drug candidates.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.

Basic Information

Product Name	1-Cyclopropylisoguanosine
CAS No.	133967-00-7
Molecular Formula	C12H15N5O4
Molecular Weight	293.28 g/mol
Synonyms	1-Cyclopropylisoguanosine; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-(cyclopropylamino)-1H-purine-2,8-dione; Cyclopropylisoguanosine; Isoguanosine, 1-cyclopropyl-; 1-Cyclopropyl-9-β-D-ribofuranosylisoguanine
EINECS	Contact for details

Quality Control

Our 1-Cyclopropylisoguanosine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) guidelines where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.