Description

1-Thyminylglucosamine-4,6-Disulfate is a chemically modified nucleoside-sugar conjugate, a derivative of glucosamine featuring a thyminyl moiety and sulfate groups. This compound is valued for its role as a key intermediate in the synthesis of novel nucleoside analogs and glycoconjugates for pharmaceutical research. It is primarily sought by researchers and manufacturers in the fields of antiviral drug development, glycobiology studies, and advanced biochemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Glycobiology Research: Used in studies exploring sulfated carbohydrate-protein interactions and cell signaling pathways.
• Bioconjugate Chemistry: Serves as a modified sugar moiety for creating targeted drug delivery systems or diagnostic probes.
• Enzyme Substrate Studies: Acts as a substrate or inhibitor for sulfotransferases and other carbohydrate-processing enzymes.
• Reference Standard: Employed as an analytical standard in quality control and method development for related APIs.

Basic Information

Item	Details
Product Name	1-Thyminylglucosamine-4,6-Disulfate
CAS No.	133906-27-1
Molecular Formula	C16H23N3O13S2
Molecular Weight	529.49 g/mol
Synonyms	1-(Thymin-1-yl)-2-deoxy-2-amino-1,4,6-tris-O-sulfo-α-D-glucopyranose; 1-(Thymin-1-yl)-2-amino-2-deoxy-α-D-glucopyranose 4,6-disulfate; Glucosamine-4,6-disulfate thyminyl derivative; Thyminyl-2-amino-2-deoxyglucoside-4,6-disulfate; 2-Amino-2-deoxy-1-(thymin-1-yl)-α-D-glucopyranose 4,6-bis(hydrogen sulfate)
EINECS	Contact for details

Quality Control

Our 1-Thyminylglucosamine-4,6-Disulfate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.